Alkyl Derivatives of Perylene Photosensitizing Antivirals: Towards Understanding the Influence of Lipophilicity

Amphipathic perylene derivatives are broad-spectrum antivirals against enveloped viruses that act as fusion inhibitors in a light-dependent manner. The compounds target the lipid bilayer of the viral envelope using the lipophilic perylene moiety and photogenerating singlet oxygen, thereby causing da...

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Detalles Bibliográficos
Autores principales: Mikhnovets, Igor E., Holoubek, Jiří, Panina, Irina S., Kotouček, Jan, Gvozdev, Daniil A., Chumakov, Stepan P., Krasilnikov, Maxim S., Zhitlov, Mikhail Y., Gulyak, Evgeny L., Chistov, Alexey A., Nikitin, Timofei D., Korshun, Vladimir A., Efremov, Roman G., Alferova, Vera A., Růžek, Daniel, Eyer, Luděk, Ustinov, Alexey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671050/
https://www.ncbi.nlm.nih.gov/pubmed/38003673
http://dx.doi.org/10.3390/ijms242216483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671050/
https://www.ncbi.nlm.nih.gov/pubmed/38003673
http://dx.doi.org/10.3390/ijms242216483

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