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Exosomal delivery of NF-κB inhibitor delays LPS-induced preterm birth and modulates fetal immune cell profile in mouse models

Accumulation of immune cells and activation of the pro-inflammatory transcription factor NF-κB in feto-maternal uterine tissues is a key feature of preterm birth (PTB) pathophysiology. Reduction of the fetal inflammatory response and NF-κB activation are key strategies to minimize infection-associat...

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Detalles Bibliográficos
Autores principales: Sheller-Miller, Samantha, Radnaa, Enkhtuya, Yoo, Jae-Kwang, Kim, Eunsoo, Choi, Kyungsun, Kim, Youngeun, Kim, Yuna, Richardson, Lauren, Choi, Chulhee, Menon, Ramkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671068/
https://www.ncbi.nlm.nih.gov/pubmed/33523942
http://dx.doi.org/10.1126/sciadv.abd3865