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Key Genes of the Immune System and Predisposition to Acquired Hemophilia A: Evidence from a Spanish Cohort of 49 Patients Using Next-Generation Sequencing

Acquired hemophilia A (AHA) is a rare bleeding disorder caused by the presence of autoantibodies against factor VIII (FVIII). As with other autoimmune diseases, its etiology is complex and its genetic basis is unknown. The aim of this study was to identify the immunogenetic background that predispos...

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Detalles Bibliográficos
Autores principales: Pardos-Gea, Jose, Martin-Fernandez, Laura, Closa, Laia, Ferrero, Ainara, Marzo, Cristina, Rubio-Rivas, Manuel, Mitjavila, Francesca, González-Porras, José Ramón, Bastida, José María, Mateo, José, Carrasco, Marina, Bernardo, Ángel, Astigarraga, Itziar, Aguinaco, Reyes, Corrales, Irene, Garcia-Martínez, Iris, Vidal, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671092/
https://www.ncbi.nlm.nih.gov/pubmed/38003562
http://dx.doi.org/10.3390/ijms242216372