Generation of a Novel SORT1×HER2 Bispecific Antibody–Drug Conjugate Targeting HER2-Low-Expression Tumor

Human epidermal growth factor receptor 2 (HER2) is considered an ideal antibody–drug conjugate (ADC) target because the gene is overexpressed in many tumors compared to normal tissues. Multiple anti-HER2 ADCs conjugated with different toxic payloads bring benefits to patients with high HER2 expressi...

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Detalles Bibliográficos
Autores principales: Zhuang, Weiliang, Zhang, Wei, Wang, Lei, Xie, Liping, Feng, Jun, Zhang, Baohong, Hu, Youjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671096/
https://www.ncbi.nlm.nih.gov/pubmed/38003245
http://dx.doi.org/10.3390/ijms242216056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671096/
https://www.ncbi.nlm.nih.gov/pubmed/38003245
http://dx.doi.org/10.3390/ijms242216056

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