SARS-CoV-2 Spike Protein Intensifies Cerebrovascular Complications in Diabetic hACE2 Mice through RAAS and TLR Signaling Activation

Diabetics are more vulnerable to SARS-CoV-2 neurological manifestations. The molecular mechanisms of SARS-CoV-2-induced cerebrovascular dysfunction in diabetes are unclear. We hypothesize that SARS-CoV-2 exacerbates diabetes-induced cerebrovascular oxidative stress and inflammation via activation of...

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Detalles Bibliográficos
Autores principales: Burnett, Faith N., Coucha, Maha, Bolduc, Deanna R., Hermanns, Veronica C., Heath, Stan P., Abdelghani, Maryam, Macias-Moriarity, Lilia Z., Abdelsaid, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671133/
https://www.ncbi.nlm.nih.gov/pubmed/38003584
http://dx.doi.org/10.3390/ijms242216394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671133/
https://www.ncbi.nlm.nih.gov/pubmed/38003584
http://dx.doi.org/10.3390/ijms242216394

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