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SARS-CoV-2 Spike Protein Intensifies Cerebrovascular Complications in Diabetic hACE2 Mice through RAAS and TLR Signaling Activation
Diabetics are more vulnerable to SARS-CoV-2 neurological manifestations. The molecular mechanisms of SARS-CoV-2-induced cerebrovascular dysfunction in diabetes are unclear. We hypothesize that SARS-CoV-2 exacerbates diabetes-induced cerebrovascular oxidative stress and inflammation via activation of...
Autores principales: | Burnett, Faith N., Coucha, Maha, Bolduc, Deanna R., Hermanns, Veronica C., Heath, Stan P., Abdelghani, Maryam, Macias-Moriarity, Lilia Z., Abdelsaid, Mohammed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671133/ https://www.ncbi.nlm.nih.gov/pubmed/38003584 http://dx.doi.org/10.3390/ijms242216394 |
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