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Development of Apoptotic-Cell-Inspired Antibody–Drug Conjugate for Effective Immune Modulation

Background: Apoptotic cells’ phosphoserine (PS) groups have a significant immunosuppressive effect. They inhibit proinflammatory signals by interacting with various immune cells, including macrophages, dendritic cells, and CD4(+) cells. Previously, we synthesized PS-group-immobilized polymers and ve...

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Detalles Bibliográficos
Autores principales: Lee, Gyeongwoo, Iwase, Taishu, Matsumoto, Shunsuke, Nabil, Ahmed, Ebara, Mitsuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671176/
https://www.ncbi.nlm.nih.gov/pubmed/38003225
http://dx.doi.org/10.3390/ijms242216036