Single-Nuclei Multiome (ATAC + Gene Expression) Sequencing of a Primary Canine Osteosarcoma Elucidates Intra-Tumoral Heterogeneity and Characterizes the Tumor Microenvironment

Osteosarcoma (OSA) is a highly aggressive bone tumor primarily affecting pediatric or adolescent humans and large-breed dogs. Canine OSA shares striking similarities with its human counterpart, making it an invaluable translational model for uncovering the disease’s complexities and developing novel...

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Detalles Bibliográficos
Autores principales: Nance, Rebecca L., Wang, Xu, Sandey, Maninder, Matz, Brad M., Thomas, AriAnna, Smith, Bruce F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671194/
https://www.ncbi.nlm.nih.gov/pubmed/38003552
http://dx.doi.org/10.3390/ijms242216365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671194/
https://www.ncbi.nlm.nih.gov/pubmed/38003552
http://dx.doi.org/10.3390/ijms242216365

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