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Systemic Evidence for Mitochondrial Dysfunction in Age-Related Macular Degeneration as Revealed by mtDNA Copy Number Measurements in Peripheral Blood

Mitochondrial dysfunction is a common occurrence in the aging process and is observed in diseases such as age-related macular degeneration (AMD). Increased levels of reactive oxygen species lead to damaged mitochondrial DNA (mtDNA), resulting in dysfunctional mitochondria, and, consequently, mtDNA c...

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Detalles Bibliográficos
Autores principales: Koller, Adriana, Lamina, Claudia, Brandl, Caroline, Zimmermann, Martina E., Stark, Klaus J., Weissensteiner, Hansi, Würzner, Reinhard, Heid, Iris M., Kronenberg, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671207/
https://www.ncbi.nlm.nih.gov/pubmed/38003595
http://dx.doi.org/10.3390/ijms242216406