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Utilizing Extraepitopic Amino Acid Substitutions to Define Changes in the Accessibility of Conformational Epitopes of the Bacillus cereus HlyII C-Terminal Domain

Hemolysin II (HlyII)—one of the pathogenic factors of Bacillus cereus, a pore-forming β-barrel toxin—possesses a C-terminal extension of 94 amino acid residues, designated as the C-terminal domain of HlyII (HlyIICTD), which plays an important role in the functioning of the toxin. Our previous work d...

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Detalles Bibliográficos
Autores principales: Rudenko, Natalia V., Nagel, Alexey S., Melnik, Bogdan S., Karatovskaya, Anna P., Vetrova, Olesya S., Zamyatina, Anna V., Andreeva-Kovalevskaya, Zhanna I., Siunov, Alexander V., Shlyapnikov, Mikhail G., Brovko, Fedor A., Solonin, Alexander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671226/
https://www.ncbi.nlm.nih.gov/pubmed/38003626
http://dx.doi.org/10.3390/ijms242216437