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Sphingosine-1-Phosphate Receptor 3 Induces Endothelial Barrier Loss via ADAM10-Mediated Vascular Endothelial-Cadherin Cleavage

Mechanical ventilation (MV) is a life-supporting strategy employed in the Intensive Care Unit (ICU). However, MV-associated mechanical stress exacerbates existing lung inflammation in ICU patients, resulting in limited improvement in mortality and a condition known as Ventilator-Induced Lung Injury...

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Detalles Bibliográficos
Autores principales: Wu, Jialin, Liang, Ying, Fu, Panfeng, Feng, Anlin, Lu, Qing, Unwalla, Hoshang J., Marciano, David P., Black, Stephen M., Wang, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671260/
https://www.ncbi.nlm.nih.gov/pubmed/38003272
http://dx.doi.org/10.3390/ijms242216083