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CRISPR-Cas9-Based Gene Knockout of Immune Checkpoints in Expanded NK Cells
Natural killer (NK) cell immunotherapy has emerged as a novel treatment modality for various cancer types, including leukemia. The modulation of inhibitory signaling pathways in T cells and NK cells has been the subject of extensive investigation in both preclinical and clinical settings in recent y...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671270/ https://www.ncbi.nlm.nih.gov/pubmed/38003255 http://dx.doi.org/10.3390/ijms242216065 |