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CRISPR-Cas9-Based Gene Knockout of Immune Checkpoints in Expanded NK Cells

Natural killer (NK) cell immunotherapy has emerged as a novel treatment modality for various cancer types, including leukemia. The modulation of inhibitory signaling pathways in T cells and NK cells has been the subject of extensive investigation in both preclinical and clinical settings in recent y...

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Detalles Bibliográficos
Autores principales: Mohammadian Gol, Tahereh, Kim, Miso, Sinn, Ralph, Ureña-Bailén, Guillermo, Stegmeyer, Sarah, Gratz, Paul Gerhard, Zahedipour, Fatemeh, Roig-Merino, Alicia, Antony, Justin S., Mezger, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671270/
https://www.ncbi.nlm.nih.gov/pubmed/38003255
http://dx.doi.org/10.3390/ijms242216065