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Troponin and a Myopathy-Linked Mutation in TPM3 Inhibit Cofilin-2-Induced Thin Filament Depolymerization

Uniform actin filament length is required for synchronized contraction of skeletal muscle. In myopathies linked to mutations in tropomyosin (Tpm) genes, irregular thin filaments are a common feature, which may result from defects in length maintenance mechanisms. The current work investigated the ef...

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Detalles Bibliográficos
Autores principales: Robaszkiewicz, Katarzyna, Wróbel, Julia, Moraczewska, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671271/
https://www.ncbi.nlm.nih.gov/pubmed/38003645
http://dx.doi.org/10.3390/ijms242216457