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Mitochondrial GpC and CpG DNA Hypermethylation Cause Metabolic Stress-Induced Mitophagy and Cholestophagy

Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by a constant accumulation of lipids in the liver. This hepatic lipotoxicity is associated with a dysregulation of the first step in lipid catabolism, known as beta oxidation, which occurs in the mitochondrial matrix....

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Detalles Bibliográficos
Autores principales: Theys, Claudia, Ibrahim, Joe, Mateiu, Ligia, Mposhi, Archibold, García-Pupo, Laura, De Pooter, Tim, De Rijk, Peter, Strazisar, Mojca, İnce, İkbal Agah, Vintea, Iuliana, Rots, Marianne G., Vanden Berghe, Wim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671279/
https://www.ncbi.nlm.nih.gov/pubmed/38003603
http://dx.doi.org/10.3390/ijms242216412