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Conformational States of the CXCR4 Inhibitor Peptide EPI-X4—A Theoretical Analysis

EPI-X4, an endogenous peptide inhibitor, has exhibited potential as a blocker of CXCR4—a G protein-coupled receptor. This unique inhibitor demonstrates the ability to impede HIV-1 infection and halt CXCR4-dependent processes such as tumor cell migration and invagination. Despite its promising effect...

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Detalles Bibliográficos
Autores principales: Jung, Christoph Karsten, Münch, Jan, Jacob, Timo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671355/
https://www.ncbi.nlm.nih.gov/pubmed/38003419
http://dx.doi.org/10.3390/ijms242216229