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Conformational States of the CXCR4 Inhibitor Peptide EPI-X4—A Theoretical Analysis
EPI-X4, an endogenous peptide inhibitor, has exhibited potential as a blocker of CXCR4—a G protein-coupled receptor. This unique inhibitor demonstrates the ability to impede HIV-1 infection and halt CXCR4-dependent processes such as tumor cell migration and invagination. Despite its promising effect...
Autores principales: | Jung, Christoph Karsten, Münch, Jan, Jacob, Timo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671355/ https://www.ncbi.nlm.nih.gov/pubmed/38003419 http://dx.doi.org/10.3390/ijms242216229 |
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