In Silico and In Vitro Study towards the Rational Design of 4,4′-Disarylbisthiazoles as a Selective α-Synucleinopathy Biomarker

The α-synucleinopathies are a group of neurodegenerative diseases characterized by the deposition of α-synuclein aggregates (α-syn) in the brain. Currently, there is no suitable tracer to enable a definitive early diagnosis of these diseases. We reported candidates based on 4,4′-disarylbisthiazole (...

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Detalles Bibliográficos
Autores principales: Uzuegbunam, Bright C., Li, Junhao, Paslawski, Wojciech, Weber, Wolfgang, Svenningsson, Per, Ågren, Hans, Hooshyar Yousefi, Behrooz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671360/
https://www.ncbi.nlm.nih.gov/pubmed/38003637
http://dx.doi.org/10.3390/ijms242216445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671360/
https://www.ncbi.nlm.nih.gov/pubmed/38003637
http://dx.doi.org/10.3390/ijms242216445

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