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In Silico and In Vitro Study towards the Rational Design of 4,4′-Disarylbisthiazoles as a Selective α-Synucleinopathy Biomarker
The α-synucleinopathies are a group of neurodegenerative diseases characterized by the deposition of α-synuclein aggregates (α-syn) in the brain. Currently, there is no suitable tracer to enable a definitive early diagnosis of these diseases. We reported candidates based on 4,4′-disarylbisthiazole (...
Autores principales: | Uzuegbunam, Bright C., Li, Junhao, Paslawski, Wojciech, Weber, Wolfgang, Svenningsson, Per, Ågren, Hans, Hooshyar Yousefi, Behrooz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671360/ https://www.ncbi.nlm.nih.gov/pubmed/38003637 http://dx.doi.org/10.3390/ijms242216445 |
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