Sulfated Polysaccharides as a Fighter with Protein Non-Physiological Aggregation: The Role of Polysaccharide Flexibility and Charge Density

Proteins can lose native functionality due to non-physiological aggregation. In this work, we have shown the power of sulfated polysaccharides as a natural assistant to restore damaged protein structures. Protein aggregates enriched by cross-β structures are a characteristic of amyloid fibrils relat...

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Detalles Bibliográficos
Autores principales: Makshakova, Olga N., Bogdanova, Liliya R., Faizullin, Dzhigangir A., Ermakova, Elena A., Zuev, Yuriy F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671430/
https://www.ncbi.nlm.nih.gov/pubmed/38003413
http://dx.doi.org/10.3390/ijms242216223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671430/
https://www.ncbi.nlm.nih.gov/pubmed/38003413
http://dx.doi.org/10.3390/ijms242216223

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