New Derivatives of N-Hydroxybutanamide: Preparation, MMP Inhibition, Cytotoxicity, and Antitumor Activity

Using a novel method of N-substituted succinimide ring opening, new N-hydroxybutanamide derivatives were synthesized. These compounds were evaluated for their ability to inhibit matrix metalloproteinases (MMPs) and their cytotoxicity. The iodoaniline derivative of N(1)-hydroxy-N(4)-phenylbutanediami...

Descripción completa

Detalles Bibliográficos
Autores principales: Balakina, Anastasia, Gadomsky, Svyatoslav, Kokovina, Tatyana, Sashenkova, Tatyana, Mishchenko, Denis, Terentiev, Alexei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671431/
https://www.ncbi.nlm.nih.gov/pubmed/38003553
http://dx.doi.org/10.3390/ijms242216360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671431/
https://www.ncbi.nlm.nih.gov/pubmed/38003553
http://dx.doi.org/10.3390/ijms242216360

Ejemplares similares