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New Derivatives of N-Hydroxybutanamide: Preparation, MMP Inhibition, Cytotoxicity, and Antitumor Activity

Using a novel method of N-substituted succinimide ring opening, new N-hydroxybutanamide derivatives were synthesized. These compounds were evaluated for their ability to inhibit matrix metalloproteinases (MMPs) and their cytotoxicity. The iodoaniline derivative of N(1)-hydroxy-N(4)-phenylbutanediami...

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Detalles Bibliográficos
Autores principales:	Balakina, Anastasia, Gadomsky, Svyatoslav, Kokovina, Tatyana, Sashenkova, Tatyana, Mishchenko, Denis, Terentiev, Alexei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671431/ https://www.ncbi.nlm.nih.gov/pubmed/38003553 http://dx.doi.org/10.3390/ijms242216360

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