Identification of a Pentasaccharide Lead Compound with High Affinity to the SARS-CoV-2 Spike Protein via In Silico Screening

The spike (S) protein on the surface of the SARS-CoV-2 virus is critical to mediate fusion with the host cell membrane through interaction with angiotensin-converting enzyme 2 (ACE2). Additionally, heparan sulfate (HS) on the host cell surface acts as an attachment factor to facilitate the binding o...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Binjie, Zhang, Tianji, Cao, Hui, Ferro, Vito, Li, Jinping, Yu, Mingjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671481/
https://www.ncbi.nlm.nih.gov/pubmed/38003304
http://dx.doi.org/10.3390/ijms242216115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671481/
https://www.ncbi.nlm.nih.gov/pubmed/38003304
http://dx.doi.org/10.3390/ijms242216115

Ejemplares similares