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Identification of a Pentasaccharide Lead Compound with High Affinity to the SARS-CoV-2 Spike Protein via In Silico Screening

The spike (S) protein on the surface of the SARS-CoV-2 virus is critical to mediate fusion with the host cell membrane through interaction with angiotensin-converting enzyme 2 (ACE2). Additionally, heparan sulfate (HS) on the host cell surface acts as an attachment factor to facilitate the binding o...

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Detalles Bibliográficos
Autores principales:	Li, Binjie, Zhang, Tianji, Cao, Hui, Ferro, Vito, Li, Jinping, Yu, Mingjia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671481/ https://www.ncbi.nlm.nih.gov/pubmed/38003304 http://dx.doi.org/10.3390/ijms242216115

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