Development of Novel Epigenetic Anti-Cancer Therapy Targeting TET Proteins

Epigenetic dysregulation, particularly alterations in DNA methylation and hydroxymethylation, plays a pivotal role in cancer initiation and progression. Ten-eleven translocation (TET) proteins catalyze the successive oxidation of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) and further o...

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Detalles Bibliográficos
Autores principales: Kim, Hyejin, Jung, Inkyung, Lee, Chan Hyeong, An, Jungeun, Ko, Myunggon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671484/
https://www.ncbi.nlm.nih.gov/pubmed/38003566
http://dx.doi.org/10.3390/ijms242216375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671484/
https://www.ncbi.nlm.nih.gov/pubmed/38003566
http://dx.doi.org/10.3390/ijms242216375

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