Effects of Remimazolam on Intracellular Calcium Dynamics in Myotubes Derived from Patients with Malignant Hyperthermia and Functional Analysis of Type 1 Ryanodine Receptor Gene Variants

Remimazolam is a novel general anesthetic and its safety in patients with malignant hyperthermia (MH) is unknown. We used myotubes derived from the skeletal muscle of patients with MH to examine the response to ryanodine receptor 1 (RYR1) agonist and remimazolam in MH-susceptible patients. Patients...

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Detalles Bibliográficos
Autores principales: Miyoshi, Hirotsugu, Otsuki, Sachiko, Mukaida, Keiko, Kido, Kenshiro, Sumii, Ayako, Ikeda, Tsuyoshi, Noda, Yuko, Yasuda, Toshimichi, Narasaki, Soshi, Kato, Takahiro, Kamiya, Satoshi, Horikawa, Yousuke T., Tsutsumi, Yasuo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671487/
https://www.ncbi.nlm.nih.gov/pubmed/38002952
http://dx.doi.org/10.3390/genes14112009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671487/
https://www.ncbi.nlm.nih.gov/pubmed/38002952
http://dx.doi.org/10.3390/genes14112009

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