scAAV2-Mediated Expression of Thioredoxin 2 and C3 Transferase Prevents Retinal Ganglion Cell Death and Lowers Intraocular Pressure in a Mouse Model of Glaucoma

Elevated intraocular pressure (IOP) in glaucoma causes retinal ganglion cell (RGC) loss and damage to the optic nerve. Although IOP is controlled pharmacologically, no treatment is available to restore retinal and optic nerve function. In this paper, we aimed to develop a novel gene therapy for glau...

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Detalles Bibliográficos
Autores principales: Kim, Hee Jong, Cha, Seho, Choi, Jun-Sub, Lee, Joo Yong, Kim, Ko Eun, Kim, Jin Kwon, Kim, Jin, Moon, Seo Yun, Lee, Steven Hyun Seung, Park, Keerang, Won, So-Yoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671512/
https://www.ncbi.nlm.nih.gov/pubmed/38003443
http://dx.doi.org/10.3390/ijms242216253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671512/
https://www.ncbi.nlm.nih.gov/pubmed/38003443
http://dx.doi.org/10.3390/ijms242216253

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