CRISPR/Cas9 Directed Reprogramming of iPSC for Accelerated Motor Neuron Differentiation Leads to Dysregulation of Neuronal Fate Patterning and Function

Neurodegeneration causes a significant disease burden and there are few therapeutic interventions available for reversing or slowing the disease progression. Induced pluripotent stem cells (iPSCs) hold significant potential since they are sourced from adult tissue and have the capacity to be differe...

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Detalles Bibliográficos
Autores principales: Davis-Anderson, Katie, Micheva-Viteva, Sofiya, Solomon, Emilia, Hovde, Blake, Cirigliano, Elisa, Harris, Jennifer, Twary, Scott, Iyer, Rashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671572/
https://www.ncbi.nlm.nih.gov/pubmed/38003351
http://dx.doi.org/10.3390/ijms242216161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671572/
https://www.ncbi.nlm.nih.gov/pubmed/38003351
http://dx.doi.org/10.3390/ijms242216161

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