Identification of CDK1, PBK, and CHEK1 as an Oncogenic Signature in Glioblastoma: A Bioinformatics Approach to Repurpose Dapagliflozin as a Therapeutic Agent

Glioblastoma multiforme (GBM) is the most aggressive and lethal primary brain tumor whose median survival is less than 15 months. The current treatment regimen comprising surgical resectioning, chemotherapy with Temozolomide (TMZ), and adjuvant radiotherapy does not achieve total patient cure. Stem...

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Detalles Bibliográficos
Autores principales: Chinyama, Harold A., Wei, Li, Mokgautsi, Ntlotlang, Lawal, Bashir, Wu, Alexander T. H., Huang, Hsu-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671581/
https://www.ncbi.nlm.nih.gov/pubmed/38003585
http://dx.doi.org/10.3390/ijms242216396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671581/
https://www.ncbi.nlm.nih.gov/pubmed/38003585
http://dx.doi.org/10.3390/ijms242216396

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