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STAT3 Signalling Drives LDH Up-Regulation and Adiponectin Down-Regulation in Cachectic Adipocytes

Cachexia is a devastating pathology that worsens the quality of life and antineoplastic treatment outcomes of oncologic patients. Herein, we report that the secretome from murine colon carcinoma CT26 induces cachectic features in both murine and human adipocytes that are associated with metabolic al...

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Detalles Bibliográficos
Autores principales: Mannelli, Michele, Bartoloni, Bianca, Cantini, Giulia, Nencioni, Elena, Magherini, Francesca, Luconi, Michaela, Modesti, Alessandra, Gamberi, Tania, Fiaschi, Tania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671608/
https://www.ncbi.nlm.nih.gov/pubmed/38003534
http://dx.doi.org/10.3390/ijms242216343