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Face and Predictive Validity of MI-RAT (Montreal Induction of Rat Arthritis Testing), a Surgical Model of Osteoarthritis Pain in Rodents Combined with Calibrated Exercise

Validating animal pain models is crucial to enhancing translational research and response to pharmacological treatment. This study investigated the effects of a calibrated slight exercise protocol alone or combined with multimodal analgesia on sensory sensitivity, neuroproteomics, and joint structur...

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Detalles Bibliográficos
Autores principales: Otis, Colombe, Bouet, Emilie, Keita-Alassane, Sokhna, Frezier, Marilyn, Delsart, Aliénor, Guillot, Martin, Bédard, Agathe, Pelletier, Jean-Pierre, Martel-Pelletier, Johanne, Lussier, Bertrand, Beaudry, Francis, Troncy, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671647/
https://www.ncbi.nlm.nih.gov/pubmed/38003530
http://dx.doi.org/10.3390/ijms242216341