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Inactivation of Group 1B Phospholipase A(2) Enhances Disease Recovery and Reduces Experimental Colitis in Mice

Phospholipase A(2) (PLA(2)) enzymes influence inflammatory bowel disease in both positive and negative manners depending on the type of PLA(2) that is expressed. This study explored the influence of the abundantly expressed Group 1B PLA(2) (PLA2G1B) on ulcerative colitis. Wild-type C57BL/6J mice and...

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Detalles Bibliográficos
Autores principales: Haller, April M., Wolfkiel, Patrick R., Jaeschke, Anja, Hui, David Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671771/
https://www.ncbi.nlm.nih.gov/pubmed/38003345
http://dx.doi.org/10.3390/ijms242216155