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Cancer Associated PRDM9: Implications for Linking Genomic Instability and Meiotic Recombination

The PR domain-containing 9 or PRDM9 is a gene recognized for its fundamental role in meiosis, a process essential for forming reproductive cells. Recent findings have implicated alterations in the PRDM9, particularly its zinc finger motifs, in the onset and progression of cancer. This association is...

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Detalles Bibliográficos
Autores principales: Ladias, Paris, Markopoulos, Georgios S., Kostoulas, Charilaos, Bouba, Ioanna, Markoula, Sofia, Georgiou, Ioannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10671843/
https://www.ncbi.nlm.nih.gov/pubmed/38003713
http://dx.doi.org/10.3390/ijms242216522