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Accurate prediction of HLA class II antigen presentation across all loci using tailored data acquisition and refined machine learning

Accurate prediction of antigen presentation by human leukocyte antigen (HLA) class II molecules is crucial for rational development of immunotherapies and vaccines targeting CD4(+) T cell activation. So far, most prediction methods for HLA class II antigen presentation have focused on HLA-DR because...

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Detalles Bibliográficos
Autores principales: Nilsson, Jonas B., Kaabinejadian, Saghar, Yari, Hooman, Kester, Michel G. D., van Balen, Peter, Hildebrand, William H., Nielsen, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10672173/
https://www.ncbi.nlm.nih.gov/pubmed/38000035
http://dx.doi.org/10.1126/sciadv.adj6367