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Indole Diterpenes from Mangrove Sediment-Derived Fungus Penicillium sp. UJNMF0740 Protect PC12 Cells against 6-OHDA-Induced Neurotoxicity via Regulating the PI3K/Akt Pathway

In our chemical investigation into Penicillium sp. UJNMF0740 derived from mangrove sediment, fourteen indole diterpene analogs, including four new ones, are purified by multiple chromatographic separation methods, with their structures being elucidated by the analyses of NMR, HR-ESIMS, and ECD data....

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Detalles Bibliográficos
Autores principales: Wang, Xin-Xin, Chen, Ze-Long, Zhang, Jun-Sheng, Liu, Hai-Shan, Ma, Ruo-Ping, Liu, Xin-Ping, Li, Ming-Yue, Ge, Di, Bao, Jie, Zhang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10672321/
https://www.ncbi.nlm.nih.gov/pubmed/37999417
http://dx.doi.org/10.3390/md21110593