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Platelet Cyclic GMP Levels Are Reduced in Patients with Primary Aldosteronism

Background and aim: Nitric oxide inhibits platelet aggregation by increasing the second messenger cyclic guanosine-3′,5′-monophosphate (cGMP) through the activation of soluble guanylyl cyclase in target cells. Within this context, the oxidative stress associated with the aldosterone excess impairs t...

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Detalles Bibliográficos
Autores principales: Sala, Carla, Rescaldani, Marta, Gherbesi, Elisa, Bolla, Gianni, Cuspidi, Cesare, Ruscica, Massimiliano, Carugo, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10672647/
https://www.ncbi.nlm.nih.gov/pubmed/38002693
http://dx.doi.org/10.3390/jcm12227081