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Platelet Cyclic GMP Levels Are Reduced in Patients with Primary Aldosteronism
Background and aim: Nitric oxide inhibits platelet aggregation by increasing the second messenger cyclic guanosine-3′,5′-monophosphate (cGMP) through the activation of soluble guanylyl cyclase in target cells. Within this context, the oxidative stress associated with the aldosterone excess impairs t...
Autores principales: | Sala, Carla, Rescaldani, Marta, Gherbesi, Elisa, Bolla, Gianni, Cuspidi, Cesare, Ruscica, Massimiliano, Carugo, Stefano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10672647/ https://www.ncbi.nlm.nih.gov/pubmed/38002693 http://dx.doi.org/10.3390/jcm12227081 |
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