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Influence of Brain Metastasis on Analgesia-Related Outcomes in Patients with Lung and Breast Cancers Treated with Naldemedine: A Propensity Score-Matched Analysis

Naldemedine is structurally designed to prevent passage across the blood–brain barrier (BBB), resulting in the attenuation of opioid-induced constipation without interfering with the analgesic effects of opioids. However, the influence of brain metastasis (BM), as one indicator of BBB disruption, on...

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Detalles Bibliográficos
Autores principales: Hanamoto, Aya, Koseki, Takenao, Utsunomiya, Ayaka, Ishihara, Takuma, Tobe, Takao, Kondo, Masashi, Kijima, Yuko, Matsuoka, Hiroshi, Mizuno, Tomohiro, Hayashi, Takahiro, Yamada, Shigeki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10672656/
https://www.ncbi.nlm.nih.gov/pubmed/38002612
http://dx.doi.org/10.3390/jcm12226997