SUMOylation of Bonus, the Drosophila homolog of Transcription Intermediary Factor 1, safeguards germline identity by recruiting repressive chromatin complexes to silence tissue-specific genes

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The conserved family of Transcription Intermediary Factors (TIF1) proteins consists of key transcriptional regulators that control transcription of target genes by modulating chromatin state. Unlike mammals that have four TIF1 members, Drosophila only encodes one member of the family, Bonus. Bonus h...

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Detalles Bibliográficos
Autores principales: Godneeva, Baira, Ninova, Maria, Fejes-Toth, Katalin, Aravin, Alexei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10672805/
https://www.ncbi.nlm.nih.gov/pubmed/37999956
http://dx.doi.org/10.7554/eLife.89493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10672805/
https://www.ncbi.nlm.nih.gov/pubmed/37999956
http://dx.doi.org/10.7554/eLife.89493

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