Reconstruction of the Steroid 1(2)-Dehydrogenation System from Nocardioides simplex VKM Ac-2033D in Mycolicibacterium Hosts

Microbial 1(2)-dehydrogenation of 3-ketosteroids is an important basis for the production of many steroid pharmaceuticals and synthons. When using the wild-type strains for whole cell catalysis, the undesirable reduction of the 20-carbonyl group, or 1(2)-hydrogenation, was observed. In this work, th...

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Detalles Bibliográficos
Autores principales: Fufaeva, Svetlana R., Dovbnya, Dmitry V., Ivashina, Tanya V., Shutov, Andrei A., Donova, Marina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10672877/
https://www.ncbi.nlm.nih.gov/pubmed/38004731
http://dx.doi.org/10.3390/microorganisms11112720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10672877/
https://www.ncbi.nlm.nih.gov/pubmed/38004731
http://dx.doi.org/10.3390/microorganisms11112720

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