In Silico and In Vitro Search for Dual Inhibitors of the Trypanosoma brucei and Leishmania major Pteridine Reductase 1 and Dihydrofolate Reductase

The parasites Trypanosoma brucei (Tb) and Leishmania major (Lm) cause the tropical diseases sleeping sickness, nagana, and cutaneous leishmaniasis. Every year, millions of humans, as well as animals, living in tropical to subtropical climates fall victim to these illnesses’ health threats. The paras...

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Detalles Bibliográficos
Autores principales: Possart, Katharina, Herrmann, Fabian C., Jose, Joachim, Schmidt, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673058/
https://www.ncbi.nlm.nih.gov/pubmed/38005256
http://dx.doi.org/10.3390/molecules28227526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673058/
https://www.ncbi.nlm.nih.gov/pubmed/38005256
http://dx.doi.org/10.3390/molecules28227526

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