New Adamantane-Containing Edaravone Conjugates as Potential Neuroprotective Agents for ALS Treatments

Currently, there are no effective drugs for the treatment of amyotrophic lateral sclerosis (ALS). Only two drugs—edaravone and riluzole—have been approved, but they have very limited efficacy. The aim of this work was to modify the structural core of the Edaravone—phenylpyrazolone moiety and combine...

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Detalles Bibliográficos
Autores principales: Lapshina, Maria A., Shevtsova, Elena F., Grigoriev, Vladimir V., Aksinenko, Aleksey Yu., Ustyugov, Aleksey A., Steinberg, Daniil A., Maleev, Grigoriy V., Dubrovskaya, Elena S., Goreva, Tatiana V., Epishina, Tatiana A., Zamoyski, Vladimir L., Makhaeva, Galina F., Fisenko, Vladimir P., Veselov, Ivan M., Vinogradova, Daria V., Bachurin, Sergey O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673157/
https://www.ncbi.nlm.nih.gov/pubmed/38005288
http://dx.doi.org/10.3390/molecules28227567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673157/
https://www.ncbi.nlm.nih.gov/pubmed/38005288
http://dx.doi.org/10.3390/molecules28227567

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