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Membrane-Mediated Cooperative Interactions of CD47 and SIRPα
The specific binding of the ubiquitous ‘marker of self’ protein CD47 to the SIRP [Formula: see text] protein anchored in the macrophage plasma membrane results in the inhibition of the engulfment of ‘self’ cells by macrophages and thus constitutes a key checkpoint of our innate immune system. Conseq...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673186/ https://www.ncbi.nlm.nih.gov/pubmed/37999357 http://dx.doi.org/10.3390/membranes13110871 |