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Metabolic Transformation of Gentiopicrin, a Liver Protective Active Ingredient, Based on Intestinal Bacteria

Gentiopicrin, the main component of the famous Chinese patent medicine Long Dan Xie Gan Wan, has the characteristics of fast absorption in vivo and low bioavailability. Intestinal bacteria play an important role in the absorption and pharmacokinetics of oral drugs. In this study, the metabolic trans...

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Detalles Bibliográficos
Autores principales: Fu, Jie, Yu, Hang, Guo, Qinglan, Wang, Yanan, Xu, Hui, Lu, Jinyue, Hu, Jiachun, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673279/
https://www.ncbi.nlm.nih.gov/pubmed/38005297
http://dx.doi.org/10.3390/molecules28227575