Identification of Dual-Target Inhibitors for Epidermal Growth Factor Receptor and AKT: Virtual Screening Based on Structure and Molecular Dynamics Study

Epidermal growth factor EGFR is an important target for non-small cell lung (NSCL) cancer, and inhibitors of the AKT protein have been used in many cancer treatments, including those for NSCL cancer. Therefore, searching small molecular inhibitors which can target both EGFR and AKT may help cancer t...

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Detalles Bibliográficos
Autores principales: Yang, Hanyu, Zhang, Zhiwei, Liu, Qian, Yu, Jie, Liu, Chongjin, Lu, Wencai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673407/
https://www.ncbi.nlm.nih.gov/pubmed/38005329
http://dx.doi.org/10.3390/molecules28227607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673407/
https://www.ncbi.nlm.nih.gov/pubmed/38005329
http://dx.doi.org/10.3390/molecules28227607

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