In Vitro and In Vivo Biological Evaluation of Indole-thiazolidine-2,4-dione Derivatives as Tyrosinase Inhibitors

Tyrosinase is an important rate-limiting enzyme in melanin biosynthesis. To find potential tyrosinase inhibitors with anti-melanogenic activity, a series of indole-thiazolidine-2,4-dione derivatives 5a~5z were synthesized by incorporating indole with thiazolidine-2,4-dione into one compound and assa...

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Detalles Bibliográficos
Autores principales: Lu, Li, Hu, Chunmei, Min, Xiaofeng, Liu, Zhong, Xu, Xuetao, Gan, Lishe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673563/
https://www.ncbi.nlm.nih.gov/pubmed/38005192
http://dx.doi.org/10.3390/molecules28227470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673563/
https://www.ncbi.nlm.nih.gov/pubmed/38005192
http://dx.doi.org/10.3390/molecules28227470

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