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In Vitro and In Vivo Biological Evaluation of Indole-thiazolidine-2,4-dione Derivatives as Tyrosinase Inhibitors

Tyrosinase is an important rate-limiting enzyme in melanin biosynthesis. To find potential tyrosinase inhibitors with anti-melanogenic activity, a series of indole-thiazolidine-2,4-dione derivatives 5a~5z were synthesized by incorporating indole with thiazolidine-2,4-dione into one compound and assa...

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Detalles Bibliográficos
Autores principales:	Lu, Li, Hu, Chunmei, Min, Xiaofeng, Liu, Zhong, Xu, Xuetao, Gan, Lishe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673563/ https://www.ncbi.nlm.nih.gov/pubmed/38005192 http://dx.doi.org/10.3390/molecules28227470

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