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In Silico and In Vitro Exploration of Poziotinib and Olmutinib Synergy in Lung Cancer: Role of hsa-miR-7-5p in Regulating Apoptotic Pathway Marker Genes

Background and objectives: Non-small cell lung cancer (NSCLC) is often caused by EGFR mutations, leading to overactive cell growth pathways. Drug resistance is a significant challenge in lung cancer treatment, affecting therapy effectiveness and patient survival. However, combining drugs in research...

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Detalles Bibliográficos
Autores principales: Alamery, Salman, AlAjmi, Anfal, Wani, Tanveer A., Zargar, Seema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673591/
https://www.ncbi.nlm.nih.gov/pubmed/38003971
http://dx.doi.org/10.3390/medicina59111923