IGF2 Peptide-Based LYTACs for Targeted Degradation of Extracellular and Transmembrane Proteins

Lysosome-targeting chimeras (LYTACs) have recently been developed to facilitate the lysosomal degradation of specific extracellular and transmembrane molecular targets. However, the LYTAC particles described to date are based on glycopeptide conjugates, which are difficult to prepare and produce on...

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Detalles Bibliográficos
Autores principales: Mikitiuk, Michał, Barczyński, Jan, Bielski, Przemysław, Arciniega, Marcelino, Tyrcha, Urszula, Hec, Aleksandra, Lipińska, Andrea D., Rychłowski, Michał, Holak, Tad A., Sitar, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673611/
https://www.ncbi.nlm.nih.gov/pubmed/38005242
http://dx.doi.org/10.3390/molecules28227519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673611/
https://www.ncbi.nlm.nih.gov/pubmed/38005242
http://dx.doi.org/10.3390/molecules28227519

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