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Increasing NPYergic transmission in the hippocampus rescues aging-related deficits of long-term potentiation in the mouse dentate gyrus

Loss of neuropeptide Y (NPY)-expressing interneurons in the hippocampus and decaying cholinergic neuromodulation are thought to contribute to impaired cognitive function during aging. However, the interaction of these two neuromodulatory systems in maintaining hippocampal synaptic plasticity during...

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Detalles Bibliográficos
Autores principales: Klinger, Katharina, del Ángel, Miguel, Çalışkan, Gürsel, Stork, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673643/
https://www.ncbi.nlm.nih.gov/pubmed/38020778
http://dx.doi.org/10.3389/fnagi.2023.1283581