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Normofractionated irradiation and not temozolomide modulates the immunogenic and oncogenic phenotype of human glioblastoma cell lines

PURPOSE: Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor, with an overall poor prognosis after diagnosis. Conventional treatment includes resection, chemotherapy with temozolomide (TMZ), and concomitant radiotherapy (RT). The recent success of immunotherapy approaches in oth...

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Detalles Bibliográficos
Autores principales: Schatz, Julia, Ladinig, Alexandra, Fietkau, Rainer, Putz, Florian, Gaipl, Udo S., Frey, Benjamin, Derer, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673751/
https://www.ncbi.nlm.nih.gov/pubmed/36480032
http://dx.doi.org/10.1007/s00066-022-02028-8